Presolol 200 (labetalol 200 mg) tablets, used to treat all grades of hypertension, are in shortage due to manufacturing issues.
The previous shortage of the 100 mg strength of Presolol tablets resolved in December 2025.
To ensure ongoing access to this essential medicine, we have approved the supply of overseas-registered labetalol hydrochloride 200 mg tablets under section 19A of the Therapeutic Goods Act 1989.
We have also made a new Serious Scarcity Substitution Instrument (SSSI). This will allow a pharmacist to dispense the different strength of the labetalol tablets prescribed in an equivalent quantity, if appropriate, without a new prescription.
Using the SSSI, if Presolol 200 (labetalol 200 mg) is prescribed but is unavailable, Presolol 100 (labetalol 100 mg) tablets can be dispensed. If Presolol 100 is prescribed but is unavailable, Presolol 200 tablets can be dispensed.
Please visit our About the shortage of Presolol (labetalol hydrochloride) tablets webpage for comprehensive information about the shortage, the overseas-registered alternative and the SSSI for pharmacists, prescribers and patients.