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Mekinist Novartis Pharmaceuticals Australia Pty Ltd

Product name
Mekinist
Accepted date
Dec-2025
Active ingredients
trametinib dimethyl sulfoxide
Proposed indication
MEKINIST, used together with dabrafenib, is proposed as a treatment for adults with a type of thyroid cancer called differentiated thyroid cancer (with a change in the BRAF V600E gene) that has spread or cannot be removed with surgery. It is proposed for patients that do not respond to radioactive iodine treatment, or cannot receive it, and whose cancer has continued to progress after previous treatments
Application type
C (new indication)
Publication date
Dec-2025