You are here

Antidepressant utilisation and risk of suicide in young people

Safety investigation
28 April 2021
Download Antidepressant utilisation and risk of suicide in young people


This revised report updates the original document published on 9 December 2020, responding to feedback received about the initial publication. The TGA's safety investigation was conducted in response to a review article by Whitely, Raven, and Jureidini, in July 2020 that identified a decade-long pattern of increasing antidepressant use and increasing rate of suicide in young Australians. The aims of this safety investigation were to assess:

  1. The strength of the current evidence for a causal association between prescribing of antidepressants and rates of youth suicide;
  2. The international regulatory landscape with respect to use of antidepressants in children and adolescents and risk minimisation;
  3. The current role of antidepressants in clinical practice for the treatment of psychiatric and developmental disorders in young people in Australia; and
  4. Whether the current risk minimisation measures in place in Australia are adequate.

We aim to provide documents in an accessible format. If you are having problems using a document with your accessibility tools, please contact us for help.