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Antidepressant utilisation and risk of suicide in young people

Safety investigation
9 December 2020
Download Antidepressant utilisation and risk of suicide in young people


This safety investigation was conducted by the Therapeutic Goods Administration (TGA) in response to a review article by Whitely, Raven, and Jureidini, in July 2020 that postulated that increased antidepressant prescribing has resulted in an increased rate of suicide in young people in Australia.

The aims of this safety investigation were to assess:

  1. The strength of the current evidence for a causal association between prescribing of antidepressants and rates of youth suicide;
  2. The international regulatory landscape with respect to use of antidepressants in children and adolescents and risk minimisation;
  3. The current role of antidepressants in clinical practice for the treatment of psychiatric and developmental disorders in young people in Australia; and
  4. Whether the current risk minimisation measures in place in Australia are adequate.

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