Fluconazole in Sodium Chloride injection, USP 200mg per 100mL (2mg per mL) Injection bag (Sagent, USA)

Fluconazole IV is indicated for use in adults and children for the following conditions but should be used only when fluconazole cannot be administered orally:

• Treatment of cryptococcal meningitis in patients who are unable to tolerate amphotericin B.
  NOTE: Data suggest that the clinical efficacy of fluconazole is lower than that of amphotericin B in the treatment of the acute phase of cryptococcal meningitis.
• Maintenance therapy to prevent relapse of cryptococcal meningitis in patients with AIDS.
• Treatment of oropharyngeal and oesophageal candidiasis in AIDS and other immunosuppressed patients aged 6 months and older.
• Secondary prophylaxis of oropharyngeal candidiasis in patients with HIV infection.
• Serious and life-threatening Candida infections in patients who are unable to tolerate amphotericin B.
  NOTE: It remains to be shown that fluconazole is as effective as amphotericin B in the treatment of serious and life-threatening Candida infections. Until such data are available, amphotericin B remains the drug of choice.