​Promethazine Hydrochloride Injection, USP 25mg/mL ampoules (XGen Pharmaceuticals DJB, USA)​

Promethazine Injection is indicated for the following conditions:

• Treatment of allergic reactions such as:
  • uncomplicated allergic conditions of the immediate type, e.g., pruritus, urticaria and angioedema, when oral therapy is impossible or contraindicated.
• Treatment and prevention of vomiting including:
  • motion sickness;
  • drug induced nausea;
  • prevention and control of nausea and vomiting associated with certain types of anaesthesia and surgery, such as procedures with a high incidence of post-operative vomiting (e.g., gynaecological surgery, strabismus or middle ear surgery, and electroconvulsive therapy); in patients with a past history of motion sickness or post-operative vomiting; and in patients in whom avoidance of vomiting is crucial (e.g., neurosurgery and eye surgery).

Promethazine has sedative effects and it is also used in pre-operative, post-operative and obstetric (during labour) sedation.