Mefloquine Hydrochloride Tablets 250mg (AA pharma inc., Canada)

In adults and children of more than 45 kg bodyweight: Malaria treatment: mefloquine is indicated for the treatment of acute attacks of malaria due to P. falciparum infection resistant to conventional antimalarial drugs. Following therapy of mixed P. falciparum and P. vivax malaria with mefloquine, relapse chemoprophylaxis with an 8-aminoquinoline derivative (e.g. primaquine) should be considered in order to eliminate hepatic forms of P. vivax. Malaria chemoprophylaxis:

• For travellers to countries with documented chloroquine and antifolate combination ([sulfadoxine/pyrimethamine] / [dapsone/pyrimethamine]) resistant P. falciparum malaria, who are considered to be at high risk for malaria in view of their residence or travel (of up to 3 months duration) through rural areas (between the dusk to dawn period).
• For travellers hypersensitive to sulphonamides and sulphones, who are considered to be at high risk for malaria in view of their residence or travel (of up to 3 months duration) through rural areas, (between the dusk to dawn period) in countries with high level chloroquine-resistant P. falciparum malaria