IMBRUVICA Janssen-Cilag Pty Ltd

The proposed uses for Imbruvica (ibrutinib) include:

Mantle cell lymphoma (MCL)
-after prior treatment: Used alone in adults who’ve already had treatment.
-First-time treatment: Used with other anti-cancer medicines for adults who are eligible for a stem cell transplant.

Waldenström’s macroglobulinaemia (WM), used alone for adults who:
-have had previous treatment, or
-are unsuitable for chemo-immunotherapy.
-also used rituximab.

Chronic lymphocytic leukaemia / small lymphocytic lymphoma (CLL/SLL)
-for adults who haven’t been treated before, it can be used alone or with rituximab, binutuzumab, or venetoclax.
-for adults who’ve had prior treatment, can be used alone or with bendamustine and rituximab.