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Australian Influenza Vaccine Committee (AIVC)

11 October 2013

AIVC recommendations for the composition of influenza vaccine for Australia in 2014

The Australian Influenza Vaccine Committee (AIVC) met at TGA, Canberra, on 10 October 2013, to recommend influenza viruses to be used in the composition of the influenza vaccines for 2014. During this meeting, the expert committee reviewed and evaluated data related to epidemiology, antigenic and genetic characteristics of recent influenza isolates circulating in Australia and the Southern Hemisphere, serological responses to 2012-2013 vaccines, and the availability of candidate vaccines viruses and reagents. The committee recommended that the TGA should adopt the September WHO recommendations; the trivalent influenza vaccine components for the Australian 2014 influenza season should contain the following:

  • A (H1N1): an A/California/7/2009 (H1N1) - like virus, 15 µg HA per dose
  • A (H3N2): an A/Texas/50/2012 (H3N2) - like virus*, 15 µg HA per dose
  • B: a B/Massachusetts/2/2012 - like virus, 15 µg HA per dose

Quadrivalent vaccines should contain viruses listed above, plus the additional B virus:

  • B/Brisbane/60/2008-like virus, 15 µg HA per dose.

* A/Texas/50/2012 is an A(H3N2) virus that following adaptation to growth in eggs has maintained antigenic properties similar to the majority of recently circulating cell-propagated A(H3N2) viruses including A/Victoria/361/2011.

The TGA has accepted the recommendations of the AIVC.

The TGA considers the following viruses or reassortants are suitable vaccine strains:

If other candidate vaccine viruses or reagents become available their suitability for use should be discussed with the TGA by emailing influenza.reagents@tga.gov.au.

Content last updated: Friday, 11 October 2013

Content last reviewed: Friday, 11 October 2013

Web page last updated: Thursday, 7 November 2013

URL: http://www.tga.gov.au/about/committees-aivc.htm