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Toxicity of tartrazine
Scientific review report
3. Review criteria and search terms
With the help of the TGA library, the TGA undertook a thorough search of the literature from the 1970s to the present for peer-reviewed publications dealing with the toxicity of tartrazine and consumption of tartrazine and its possible correlation with hyperactivity and behavioural changes. The search included both animal and human studies.
The review is based on several published papers (up to May 2013), as well as on reviews of international authorities in the public domain as listed in the Bibliography. The following databases were searched: TOXLINE, TOXNET, PUBMED, Medline, Embase, Biosis, and a Dialog search on a large number of medical and pharmaceutical databases.